L-368,899hydrochloride
L-368,899hydrochloride Basic information
- Product Name:
- L-368,899hydrochloride
- Synonyms:
-
- (2S)-2-Amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)butanamide
- (2S)-2-amino-N-[(1R,3S,4S)-7,7-dimethyl-4-[[4-(2-methylphenyl)piperazin-1-yl]sulfonylmethyl]-3-bicyclo[2.2.1]heptanyl]-4-methylsulfonylbutanamide
- Butanamide, 2-amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)-, (2S)-
- L-368,899 hydrochlor
- L-368899 free base
- CAS:
- 148927-60-0
- MF:
- C26H42N4O5S2
- MW:
- 554.77
- Mol File:
- 148927-60-0.mol
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L-368,899hydrochloride Chemical Properties
- storage temp.
- Store at +4°C
- solubility
- Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
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L-368,899hydrochloride Usage And Synthesis
Uses
L-368,899 Dihydrochloride is an oxytoxin antagonist and may be used in the treatment of early pregnancy failure.
Biological Activity
Potent, non-peptide and orally active oxytocin receptor antagonist (IC 50 = 8.9 nM) that displays > 40-fold selectivity over vasopressin V 1a and V 2 receptors (IC 50 values are 370 and 570 nM respectively). Antagonizes oxytocin-induced uterine contractions in vitro and in vivo .
L-368,899hydrochlorideSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Shanghai meikai technology co., ltd
- Tel
- 021-18721550-091 18721550091
- yangdong@pharma.com
Shanghai Universal Biotech Co.,Ltd
- Tel
- 18768175414
- gaojun@univ-bio.com