Basic information Safety Supplier Related

L-368,899hydrochloride

Basic information Safety Supplier Related

L-368,899hydrochloride Basic information

Product Name:
L-368,899hydrochloride
Synonyms:
  • (2S)-2-Amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)butanamide
  • (2S)-2-amino-N-[(1R,3S,4S)-7,7-dimethyl-4-[[4-(2-methylphenyl)piperazin-1-yl]sulfonylmethyl]-3-bicyclo[2.2.1]heptanyl]-4-methylsulfonylbutanamide
  • Butanamide, 2-amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)-, (2S)-
  • L-368,899 hydrochlor
  • L-368899 free base
CAS:
148927-60-0
MF:
C26H42N4O5S2
MW:
554.77
Mol File:
148927-60-0.mol
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L-368,899hydrochloride Chemical Properties

storage temp. 
Store at +4°C
solubility 
Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
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L-368,899hydrochloride Usage And Synthesis

Uses

L-368,899 Dihydrochloride is an oxytoxin antagonist and may be used in the treatment of early pregnancy failure.

Biological Activity

Potent, non-peptide and orally active oxytocin receptor antagonist (IC 50 = 8.9 nM) that displays > 40-fold selectivity over vasopressin V 1a and V 2 receptors (IC 50 values are 370 and 570 nM respectively). Antagonizes oxytocin-induced uterine contractions in vitro and in vivo .

L-368,899hydrochlorideSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
EMMX Biotechnology LLC
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888-539-0666
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info@emmx.com
TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Shanghai meikai technology co., ltd
Tel
021-18721550-091 18721550091
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yangdong@pharma.com
Shanghai Universal Biotech Co.,Ltd
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13774214275
Email
zhouzz@univ-bio.com