Basic information Safety Supplier Related

Spiraprilat

Basic information Safety Supplier Related

Spiraprilat Basic information

Product Name:
Spiraprilat
Synonyms:
  • SCH 33861
  • (3S)-2-[(S)-2-[[(S)-1-Carboxy-3-phenylpropyl]amino]propionyl]-2-aza-6,9-dithiaspiro[4.4]nonane-3-carboxylic acid
  • (8S)-7-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid
  • TI-213-864
  • 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, 7-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)-, (8S-(7(R*(R*)),8R*))-
  • Spiraprilate
  • Spiraprilate [inn-french]
  • Spiraprilatum
CAS:
83602-05-5
MF:
C20H26N2O5S2
MW:
438.566
Mol File:
83602-05-5.mol
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Spiraprilat Chemical Properties

Melting point:
163-165°
alpha 
D26 +4.1° (c = 0.4 in ethanol)
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Spiraprilat Usage And Synthesis

Definition

ChEBI: Spiraprilat is an azaspiro compound that is spirapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid group. It is the active metabolite of the angiotensin-converting enzyme (ACE) inhibitor spirapril. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a drug metabolite. It is an azaspiro compound, a dicarboxylic acid, a dipeptide, a dithioketal, a pyrrolidinecarboxylic acid, a secondary amino compound and a tertiary carboxamide.

SpiraprilatSupplier

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