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Sclareolide

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Sclareolide Basic information

Product Name:
Sclareolide
Synonyms:
  • SCLAREOLIDE
  • 1-b]furan-2(1H)-one,decahydro-3a,6,6,9a-tetramethyl-,[3aR-(3a.alpha.,5a.beta.,9a.alpha.,9b.beta.)Naphtho[2
  • Naphtho[2,1-b]furan-2(1H)-one,decahydro-3a,6,6,9a-
  • Norambreinolide
  • tetramethyl-,(3aR,5aS,9aS,9bR)-
  • Sclareolide (Dodecahydro-3a,6,6,9a,-tetramethylnaphto(2,1-b Furan–2–one)
  • Sclareolide (Dodecahydro-3a,6,6,9a,-tetramethylnaphto(2,1-b Furanne)
  • Clareolide
CAS:
564-20-5
MF:
C16H26O2
MW:
250.38
EINECS:
209-269-0
Product Categories:
  • Miscellaneous Natural Products
  • Natural Plant Extract
  • Flavors & Fragrances
  • Chiral Building Blocks
  • Flavors and Fragrances
  • Inhibitors
  • Furans
  • Heterocyclic Building Blocks
Mol File:
564-20-5.mol
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Sclareolide Chemical Properties

Melting point:
124-126 °C (lit.)
alpha 
47 º(c=2, chloroform)
Boiling point:
321.4±10.0 °C(Predicted)
Density 
1.009±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
FEMA 
3794 | SCLAREOLIDE
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly)
color 
White to Off-White
Odor
at 10.00 % in isopropyl myristate. dry paper woody ambergris labdanum
Odor Type
woody
optical activity
[α]20/D +47°, c = 2% in chloroform
Water Solubility 
10mg/L at 25℃
JECFA Number
1165
InChIKey
IMKJGXCIJJXALX-SHUKQUCYSA-N
LogP
4.5 at 25℃
NIST Chemistry Reference
Naphtho[2,1-b]furan-2(1h)-one, decahydro-3a,6,6,9a-tetramethyl-, [3ar-(3a«alpha»,5a«beta»,9a«alpha»,9b«beta»)]-(564-20-5)
EPA Substance Registry System
Naphtho[2,1-b]furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)- (564-20-5)
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Safety Information

Safety Statements 
24/25
WGK Germany 
2
HS Code 
29322090

MSDS

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Sclareolide Usage And Synthesis

Chemical Properties

Sclareolide has a musky, wood odor.

Occurrence

Reported present in clary sage bush (Salvia sclarea)

Uses

Sclareolide is found in Salvia yosgadensis and is a close analog of sclareol, an antifungal diterpene.

Uses

antimicrobial

Uses

sclareolide is a fragrancing ingredient, it can help mask formulation odors. It is synthetically manufactured.

Preparation

Sclareol, isolated from clary sage by solvent extraction, can be efficiently oxidized by the microorganism Cryptococcus albidus to sclareolide.

Definition

ChEBI: Norambreinolide is a naphthofuran.

General Description

Sclareolide is a diterpenoid compound mainly used in the perfume industry for its amber like odor.

Flammability and Explosibility

Not classified

SclareolideSupplier

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