Tiospirone Chemical Properties

form 

Solid

color 

White to off-white

Tiospirone Usage And Synthesis

Uses

Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm[1][2].

References

[1] Arolfo MP, et, al. Effects of amperozide and tiospirone, atypical antipsychotic 5-HT2 drugs, on food-reinforced behavior in rats. Physiol Behav. 1999 Dec;68(1-2):93-8. DOI:10.1016/s0031-9384(99)00141-9
[2] Arolfo MP, et, al. Tiospirone and the reinforcing effects of cocaine in the conditioned place preference paradigm in rats. J Pharm Pharmacol. 2000 Aug;52(8):977-81. DOI:10.1211/0022357001774697

Tiospirone(87691-91-6)Related Product Information

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