D-gamma-Tocotrienol Chemical Properties

Boiling point:

530.8±49.0 °C(Predicted)

Density 

0.964±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

pka

11.05±0.40(Predicted)

color 

Very Dark Yellow

Stability:

Light Sensitive

LogP

10.300 (est)

Safety Information

WGK Germany 

2

D-gamma-Tocotrienol Usage And Synthesis

Description

γ-Tocotrienol is a form of vitamin E that has been found in rice bran and has diverse biological activities. It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 , or L-buthionine-(S,R)-sulfoximine (BSO; ) in rat striatal cultures when used at concentrations ranging from 0.1 to 10 μM. γ-Tocotrienol (20 μM) induces apoptosis in malignant sympathoadrenal (+SA) mouse mammary epithelial cells. In vivo, γ-tocotrienol (15, 30, and 150 mg/kg) reduces blood pressure and plasma lipid peroxide levels in spontaneously hypertensive rats. [Matreya, LLC. Catalog No. 2111]

Chemical Properties

g:d:aTocotrienol 1.6:0.4:1

Uses

γ-Tocotrienol exhibits antioxidant properties and belongs to the vitamin E family. It is naturally found in wheat germ oil and bran. In addition, α-tocopherol and γ-tocotrienol derivatives are potential lead compounds for developing?anticancer and?antiproliferative agents against?MCF-7 and MDA-MB-231 breast cancer cells and the A549 lung cancer cells.

Definition

ChEBI: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2.

D-gamma-Tocotrienol(14101-61-2)Related Product Information

• D-gamma-Tocopherol
• D-γ-Tocotrienol-D6