(S)-(-)-Nadifloxacin Chemical Properties

Boiling point:

624.9±55.0 °C(Predicted)

Density 

1.46

storage temp. 

Store at -20°C

solubility 

DMSO : 125 mg/mL (346.86 mM; Need ultrasonic)

pka

5.55±0.40(Predicted)

form 

Solid

color 

White to off-white

(S)-(-)-Nadifloxacin Usage And Synthesis

Uses

(S)-(-)-Nadifloxacin is an anti-bacterial agent against multidrug-resistant Staphylococcus aureus. Also, it is derived from 6-Fluoro-2-methylquinoline (F595900), which is an quinoline derivative, a highly potent thrombin receptor antagonist.

Definition

ChEBI: (S)-nadifloxacin is a nadifloxacin. It is an enantiomer of a (R)-nadifloxacin.

Biological Activity

Levonadifloxacin is a potent benzoquinolizine fluoroquinolone antibiotic th at is affective against Gram-positive and Gram-negative bacteria, including methicillin- and quinolone-resistant Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, and Moraxella catarrhalis and atypical pathogens. It appears th at Levonadifloxacin targets staphylococcal DNA gyrase, unlike other quinolones, which primarily inhibit DNA topoisomerase IV.

(S)-(-)-Nadifloxacin(154357-42-3)Related Product Information

• 4-(4-HYDROXYPIPERIDIN-1-YL)BENZALDEHYDE
• Nadifloxacin
• (S)-(-)-Nadifloxacin
• Flumequine
• 1-AdaMantanethylaMine
• Levofloxacin mesylate