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MK 485

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MK 485 Basic information

Product Name:
MK 485
Synonyms:
  • Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-a-methyl-, (R)-
  • Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, (αR)-
  • Hydrocinnamic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, D- (8CI)
  • MK 485
  • R-(+)-Carbidopa
  • Benzenepropanoic acid, α-hydrazinyl-3,4-dihydroxy-α-methyl-, (αR)-
  • Carbidopa Impurity 12
  • Carbidopa Impurity 18
CAS:
28875-92-5
MF:
C10H14N2O4
MW:
226.23
Product Categories:
  • Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
  • ZJ
Mol File:
28875-92-5.mol
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MK 485 Chemical Properties

Melting point:
>163°C (dec.)
Boiling point:
528.7±50.0 °C(Predicted)
Density 
1.420±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka
3.40±0.14(Predicted)
form 
Solid
color 
Off-White to Beige
Stability:
Hygroscopic
InChI
InChI=1/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/s3
InChIKey
TZFNLOMSOLWIDK-JQHDBZEONA-N
SMILES
[C@](C)(NN)(C(=O)O)CC1C=CC(O)=C(O)C=1 |&1:0,r|
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MK 485 Usage And Synthesis

Uses

R-(+)-Carbidopa is an inhibitor of DOPA decarboxylase, which plays a significant role in the prevention of the conversion of L-DOPA (D533751) to dopamine (D533780). Studies has also indicated the inhibitory effects of towards L-DOPA in human liver prepns and as well as 5-hydroxytryptophan (H975700).

MK 485Supplier

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