Rimonabant hydrochloride Chemical Properties

Melting point:

230-240°C

storage temp. 

2-8°C

solubility 

DMSO: soluble20mg/mL, clear

form 

powder

color 

white to beige

CAS DataBase Reference

158681-13-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,Xi

Risk Statements 

25-36

Safety Statements 

26-45

RIDADR 

UN 2811 6.1 / PGIII

WGK Germany 

3

Rimonabant hydrochloride Usage And Synthesis

Chemical Properties

White to Off-White Crystalline Solid

Uses

The first of a new class of selective (Cannabinoid-1 (CB-1) receptor antagonists

Uses

A brain cannabinoid receptor (CB1) antagonist. Antiobesity agent.

Uses

Rimonabant hydrochloride has been used as an antagonist of cannabinoid 1 (CB1) receptor:

• to study its effects on protein synthesis in C2C12 myotubes
• to analyze its effects on human astroglia
• in combination with methanandamide (mAEA) to study its effects on murine gastric vagal afferent mechanosensitivity

Hazard

A poison.

Biochem/physiol Actions

Rimonabant acts as a mycobacterial membrane protein large 3 (MMPL3) inhibitor. Rimonabant hydrochloride exhibits therapeutic activity against weight reduction and smoking cessation.

storage

Desiccate at RT

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