4-Pyridinol,2-methoxy-(6CI,9CI) Chemical Properties

Density 

1.190

storage temp. 

Sealed in dry,Room Temperature

form 

solid

color 

Yellow

Safety Information

HS Code 

2933399990

4-Pyridinol,2-methoxy-(6CI,9CI) Usage And Synthesis

Synthesis

General procedure for the synthesis of 2-methoxy-4-pyridinol from 4-(benzyloxy)-2-methoxypyridine: In Example (16a), prepared 4-(benzyloxy)-2-methoxypyridine (4.65 g, 21.6 mmol) and 10% palladium carbon (2.30 g, 2.16 mmol) were dissolved in ethanol (100 mL). The mixture was stirred at room temperature for 30 minutes under hydrogen atmosphere. Upon completion of the reaction, the insoluble material was removed by filtration and the filtrate was subsequently concentrated to afford 2-methoxy-4-pyridinol (2.70 g, 99%) as a colorless oily product. Its 1H-NMR (400 MHz, CDCl3) data were as follows: δppm: 3.90 (3H, s), 6.13 (1H, s), 6.42 (1H, d, J = 5.9 Hz), 7.80 (1H, brs).

References

[1] Patent: EP2404918, 2012, A1. Location in patent: Page/Page column 34

4-Pyridinol,2-methoxy-(6CI,9CI)(66080-45-3)Related Product Information

• 3,5,6-Trichloropyrid