CS 722
CS 722 Basic information
- Product Name:
- CS 722
- Synonyms:
-
- CS 722
- 4-chloro-2-[(2R)-2-hydroxy-3-morpholin-4-ylpropyl]-5-phenyl-1,2-oxazol-3-one
- CAS:
- 144886-17-9
- MF:
- C16H19ClN2O4.ClH
- MW:
- 375.25
- Mol File:
- 144886-17-9.mol
CS 722 Usage And Synthesis
Description
CS 722 is a centrally acting muscle relaxant. CS-722 exerts its muscle relaxant action by affecting both the supraspinal structure and the spinal cord.
Uses
CS-722 is a centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents[1][2].
References
[1] Marszalec W, et al. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119(1):126-32. DOI:10.1111/j.1476-5381.1996.tb15685.x
[2] Tanabe M, et al. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313(3):187-9. DOI:10.1016/0014-2999(96)00634-6