2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Chemical Properties

Melting point:

39-41 °C(lit.)

Boiling point:

94-95 °C

Density 

1.178±0.06 g/cm3 (20 ºC 760 Torr)

Flash point:

220 °F

storage temp. 

2-8°C

form 

Crystals

color 

White to light yellow

Water Solubility 

Insoluble in water.

BRN 

1924015

InChIKey

SCOJKGRNQDKFRP-UHFFFAOYSA-N

CAS DataBase Reference

67442-07-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

23-26-27-28-37/39

WGK Germany 

3

HS Code 

29241900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Usage And Synthesis

Chemical Properties

white to light yellow crystals

Uses

2-Chloro-N-methoxy-N-methylacetamide is used in the preparation of 2-heptyl-3-hydroxy-4(1H)-quinolone (Pseudomonas quinolone signal or PQS) and structurally related 2-alkyl-4-quinolones having biological activity, 2-(benzo[d]thiazol-2-ylsulfonyl)-N-methoxy-N-methylacetamide and α-chloro-ketone, starting reagent for the one-pot synthesis of 2-heptyl-3-hydroxyl-4(1H)-quinolone (PQS), signaling molecule in the quorum sensing of Pseudomonas aeruginosa.

General Description

2-Chloro-N-methoxy-N-methylacetamide is a Weinreb amide.

2-CHLORO-N-METHOXY-N-METHYLACETAMIDE(67442-07-3)Related Product Information

• O-(4-NITROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
• N-Methylacetamide
• N-Methoxy-N-methylacetamide
• 4-CHLORO-N-METHOXY-N-METHYLACETAMIDE
• CS 722
• 1-[3A,11C-DIHYDRO-3H-BENZO[5,6]CHROMENO[4,3-C]ISOXAZOL-1(4H)-YL]-2-CHLORO-1-ETHANONE
• 2-(CHLOROACETYL)-5-METHYLISOXAZOL-3(2H)-ONE
• 2-CHLORO-N-METHOXY-N-METHYLACETAMIDE