ETHYL TRANS-4-OXO-2-BUTENOATE Chemical Properties

Melting point:

-9°C

Boiling point:

184-188°C

Density 

1,063 g/cm³

refractive index 

1.4550

Flash point:

68°C

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

Water Solubility 

Slightly soluble in water(2.6 g/L at 25°C).

BRN 

8762336

Safety Information

Risk Statements 

25-34-43

Safety Statements 

23-36/37/39-45-24/25

RIDADR 

2927

HazardClass 

8

PackingGroup 

III

HS Code 

29183000

MSDS

• Language:English Provider:ALFA

ETHYL TRANS-4-OXO-2-BUTENOATE Usage And Synthesis

Chemical Properties

Clear yellow-green liquid

Uses

Ethyl trans-4-oxo-2-butenoate is an intermediate used to synthesize pharmaceutically active molecules. It is also used in the asymmetric catalytic alkynylation of acetaldehyde, producing attractive synthons with broad applications, such as (+)-Tetrahydropyrenophorol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 3421, 1984 DOI: 10.1021/jo00192a047
Synthetic Communications, 18, p. 1913, 1988 DOI: 10.1080/00397918808068257
Tetrahedron Letters, 31, p. 2145, 1990 DOI: 10.1016/0040-4039(90)80094-3

ETHYL TRANS-4-OXO-2-BUTENOATE(2960-66-9)Related Product Information

• fumaraldehydic acid
• IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETIC ACID
• IMidazo[1,2-a]pyridine-3-aceticacid,ethylester
• 2-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)acetic acid
• trans-4-Hydroxy-D-proline
• trans-4-Phenyl-L-proline
• TRANS-4-AMINO-CYCLOHEXANE CARBOXYLIC ACID HYDROCHLORIDE
• TRANS-4-HYDROXY-D-PROLINE HYDROCHLORIDE
• TRANS-1,4-CYCLOHEXANEDIMETHANOL
• trans-2-Aminocyclopentanol hydrochloride
• 2,4,6-Octatrienedioic acid, 1,8-diethyl ester
• TETRAETHYL ETHYLENETETRACARBOXYLATE
• FUMARIC ACID MONOETHYL ESTER, MAGNESIUM SALT
• BUTOPYRONOXYL
• Monoethyl fumarate
• Diethyl oxalacetate sodium salt
• Ethyl trans-3-Benzoylacrylate
• CYTOCHALASIN A