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DULCITOL

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DULCITOL Basic information

Product Name:
DULCITOL
Synonyms:
  • 1H-Naphtho[2,1-b]pyran-1-one,3-phenyl-
  • 3-Phenyl-1H-benzo[f]chromen-1-one
  • 3-Phenyl-1H-naphtho(2,1-b)pyran-1-one
  • 3-Phenyl-1H-naphtho[2,1-b]pyran-1-one
  • 3-Phenyl-benzo[f]chromen-1-one
  • β-Naphthoflavon
  • 5,6-BENZOFLAVONE
  • β-Naphthoflavone, 99+%
CAS:
6051-87-2
MF:
C19H12O2
MW:
272.3
EINECS:
227-958-4
Product Categories:
  • Flavones
  • Phase I Enzyme Inducer
  • Phase I Enzyme Inducers
  • Benzopyrans
  • Bioactive Small Molecules
  • Building Blocks
  • Cancer Research
  • Cell Biology
  • Chemical Synthesis
  • Chemopreventive Agents
  • Heterocyclic Building Blocks
  • Multidrug Resistance
  • N
Mol File:
6051-87-2.mol
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DULCITOL Chemical Properties

Melting point:
164-166 °C (lit.)
Boiling point:
275-280 °C (1 mmHg)
Density 
1.1382 (rough estimate)
refractive index 
1.5510 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Crystalline Powder
color 
yellow to tan
BRN 
18991
LogP
5.003 (est)
CAS DataBase Reference
6051-87-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi,C,F
Risk Statements 
22-34-11
Safety Statements 
24/25-45-36/37/39-26-16
WGK Germany 
3
RTECS 
QL6200000
F 
3-10
Hazard Note 
Irritant
HS Code 
29329900

MSDS

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DULCITOL Usage And Synthesis

Chemical Properties

SLIGHTLY BEIGE CRYSTALLINE POWDER

Uses

beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.

Definition

ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.

General Description

β-Naphthoflavone is a polyaromatic hydrocarbon.

Biochem/physiol Actions

β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors.

DULCITOLSupplier

J & K SCIENTIFIC LTD.
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Energy Chemical
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021-021-58432009 400-005-6266
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