DULCITOL
DULCITOL Basic information
- Product Name:
- DULCITOL
- Synonyms:
-
- 1H-Naphtho[2,1-b]pyran-1-one,3-phenyl-
- 3-Phenyl-1H-benzo[f]chromen-1-one
- 3-Phenyl-1H-naphtho(2,1-b)pyran-1-one
- 3-Phenyl-1H-naphtho[2,1-b]pyran-1-one
- 3-Phenyl-benzo[f]chromen-1-one
- β-Naphthoflavon
- 5,6-BENZOFLAVONE
- β-Naphthoflavone, 99+%
- CAS:
- 6051-87-2
- MF:
- C19H12O2
- MW:
- 272.3
- EINECS:
- 227-958-4
- Product Categories:
-
- Flavones
- Phase I Enzyme Inducer
- Phase I Enzyme Inducers
- Benzopyrans
- Bioactive Small Molecules
- Building Blocks
- Cancer Research
- Cell Biology
- Chemical Synthesis
- Chemopreventive Agents
- Heterocyclic Building Blocks
- Multidrug Resistance
- N
- Mol File:
- 6051-87-2.mol
DULCITOL Chemical Properties
- Melting point:
- 164-166 °C (lit.)
- Boiling point:
- 275-280 °C (1 mmHg)
- Density
- 1.1382 (rough estimate)
- refractive index
- 1.5510 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Crystalline Powder
- color
- yellow to tan
- BRN
- 18991
- LogP
- 5.003 (est)
- CAS DataBase Reference
- 6051-87-2(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xn,Xi,C,F
- Risk Statements
- 22-34-11
- Safety Statements
- 24/25-45-36/37/39-26-16
- WGK Germany
- 3
- RTECS
- QL6200000
- F
- 3-10
- Hazard Note
- Irritant
- HS Code
- 29329900
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
DULCITOL Usage And Synthesis
Chemical Properties
SLIGHTLY BEIGE CRYSTALLINE POWDER
Uses
beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.
Definition
ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
General Description
β-Naphthoflavone is a polyaromatic hydrocarbon.
Biochem/physiol Actions
β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors.
DULCITOLSupplier
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
- Tel
- 021-61259108 18621169109
- market03@meryer.com
- Tel
- 400-6106006
- saleschina@alfa-asia.com
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
DULCITOL(6051-87-2)Related Product Information
- Dulcitol
- 4'-METHOXY-5,6-BENZOFLAVONE
- 2-IODO-3-PHENYL-1H-NAPHTHO[2,1-B]PYRAN-1-ONE
- 4'-HYDROXY-BETA-NAPHTHOFLAVONE
- 2'-HYDROXY-BETA-NAPHTHOFLAVONE
- 2'-METHOXY-BETA-NAPHTHOFLAVONE
- 3'-METHOXY-BETA-NAPHTHOFLAVONE
- 3',4'-DIMETHOXY-BETA-NAPHTHOFLAVONE
- DULCITOL
- 3',4'-DIHYDROXY-BETA-NAPHTHOFLAVONE
- 3'-HYDROXY-B-NAPHTHOFLAVONE
- BETA-NAPHTHOFLAVANOL