2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE Chemical Properties

Boiling point:

81.5-82 °C13 mm Hg(lit.)

Density 

1.149 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.471(lit.)

Flash point:

>230 °F

Safety Information

Hazard Codes 

C

Risk Statements 

14-34

Safety Statements 

22-26-27-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE Usage And Synthesis

Description

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent commonly used in chemical and experimental research as a reagent for the phosphorylation of alcohols and heteroatoms for the formation of glycosyl donors and ligands, and in analytical studies of derivatised lignin samples. It is also used as a catalyst in CuO/TiO2 catalysed lignin oxidation studies.

Chemical Properties

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent in the physical state of a solid. Molecular weight: 182.59, Density: 1.149 g/cm³, Boiling point: 81.5-82° C (lit.) at 13 mmHg, Flash point: 113 °C, Refractive index: n20/D 1.471 (lit.), Store at 10°C-25°C, keep dry, under inert gas nitrogen.

Uses

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (TMDP) can be used:

• As a reagent for the phosphitylation of alcohols and heteroatomic nucleophiles, resulting in the formation of useful glycosyl donors and ligands.
• As a phosphitylation reagent to derivatize lignin samples for ³¹P NMR analysis.

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE(14812-59-0)Related Product Information

• 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
• 2-Chloro-1,3,2-dioxaphospholane
• DIETHYL CHLOROPHOSPHITE