2-AMINO-5-ETHYLPYRAZINE Chemical Properties

Boiling point:

250.2±35.0 °C(Predicted)

Density 

1.109±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

3.50±0.10(Predicted)

Safety Information

HS Code 

2933998090

2-AMINO-5-ETHYLPYRAZINE Usage And Synthesis

Synthesis

Step 1: Hydrogenation reaction. 5-Ethynyl-2-aminopyrazine (18 mg, 0.151 mmol) was dissolved in ethyl acetate (500 μL) under stirring conditions and triethylamine (63 μL, 0.45 mmol) and Pd(OH)2/carbon catalyst (0.01 mmol, 20% wt on carbon) were added sequentially. The reaction system was placed in a hydrogen atmosphere at 45 psi and the reaction was shaken for 6 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the off-white solid product 2-amino-5-ethylpyrazine in 84% yield.

References

[1] Patent: US2003/69284, 2003, A1

2-AMINO-5-ETHYLPYRAZINE(13535-07-4)Related Product Information

• 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE
• 2-Amino-5-bromobenzaldehyde
• Ethylpyrazine
• 6-Biopterin
• L-MONAPTERIN
• 2-AMINO-5-ETHYLPYRAZINE
• 2-CHLORO-6-(BETA-D-2-DEOXYRIBOFURANOSYL)-3,5-DIAMINOPYRAZINE
• 5-TERT-BUTYLPYRAZIN-2-AMINE
• homofolic acid
• 2-N-ACETYL-1',2'-DI-O-ACETYL-6-BIOPTERIN
• SALOR-INT L144916-1EA
• SALOR-INT L150673-1EA
• 1,3-DIMETHYL-6-PROPYL-2,4(1H,3H)-PTERIDINEDIONE
• SPECS AE-641/09365047
• SALOR-INT L145149-1EA
• SALOR-INT L479179-1EA
• SPECS AE-641/09370008
• 5-ISOBUTYLPYRAZIN-2-AMINE