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4-Isoquinolineboronic acid

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4-Isoquinolineboronic acid Basic information

Product Name:
4-Isoquinolineboronic acid
Synonyms:
  • CHEMBRDG-BB 4002849
  • ISOQUINOLIN-5-YLBORONIC ACID
  • ISOQUINOLIN-4-YLBORONIC ACID
  • ISOQUINOLINE-4-BORONIC ACID
  • 4-ISOQUINOLINEBORONIC ACID
  • 4-ISOQUINOLINYLBORONI ACID
  • AKOS BRN-0121
  • AKOS BRN-0458
CAS:
192182-56-2
MF:
C9H8BNO2
MW:
172.98
Product Categories:
  • Boric Acid| Boric Acid Ester| Potassium Trifluoroborate
  • Boronic Acids & Esters
  • Quinolines, Isoquinolines & Quinoxalines
  • Quinoline&Isoquinoline
  • Boronic acid
  • Isoquinoline
  • blocks
  • BoronicAcids
  • Quinolines
  • Organoborons
  • Boronic Acids & Esters
  • Quinolines, Isoquinolines & Quinoxalines
Mol File:
192182-56-2.mol
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4-Isoquinolineboronic acid Chemical Properties

Melting point:
178°C
Boiling point:
419.1±37.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
solid
pka
4.61±0.30(Predicted)
color 
White to off-white
CAS DataBase Reference
192182-56-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
29349990

MSDS

  • Language:English Provider:ALFA
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4-Isoquinolineboronic acid Usage And Synthesis

Chemical Properties

Pink solid

Uses

Reactant for:

  • Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases
  • Preparation of tetrabutylammonium trifluoroborates
  • Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors
  • Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain
  • Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines
  • Synthesis of antagonists of bacterial quorum sensing
  • Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions

General Description

May contain varying amounts of anhydride

4-Isoquinolineboronic acidSupplier

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