Cevimeline Hydrochloride Salt Chemical Properties

Melting point:

195-197?C

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

Water:50.0(Max Conc. mg/mL);212.07(Max Conc. mM)

form 

A crystalline solid

color 

White to off-white

Stability:

Hygroscopic

Safety Information

Toxicity

mouse,LD50,intravenous,33mg/kg (33mg/kg),United States Patent Document. Vol. #4855290,

Cevimeline Hydrochloride Salt Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A novel muscarinic M1 and M3 receptor agonist. Sialagogue.

Biological Activity

Selective M 1 receptor agonist. Induces atropine-sensitive contractions of isolated guinea pig ilea and trachea preparations (EC 50 values are 3.5 and 3 μ M respectively). Reverses AF64A-induced cognitive impairments in vivo .

storage

-20°C

Cevimeline Hydrochloride Salt(107220-28-0)Related Product Information

• 2-Methylindole
• 4-Methyl-2-pentanone
• p-Toluidine
• Chlorotrimethylsilane
• rac-Cevimeline-d4 HCl
• rac-Cevimeline N-Glucuronide (Mixture of Diastereomers)