UNOPROSTONE
UNOPROSTONE Basic information
- Product Name:
- UNOPROSTONE
- Synonyms:
-
- UNOPROSTONE
- 9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID
- Unii-6X4F561V3w
- Unoprostone [inn]
- 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA
- (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid
- 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
- Alprostadil Impurity 20
- CAS:
- 120373-36-6
- MF:
- C22H38O5
- MW:
- 382.53
- Mol File:
- 120373-36-6.mol
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UNOPROSTONE Chemical Properties
- Boiling point:
- 562.9±40.0 °C(Predicted)
- Density
- 1.069±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 25 mg/ml; DMSO: 17 mg/ml; Ethanol: 12 mg/ml; PBS (7.2): 90 μg/ml
- pka
- 4.76±0.10(Predicted)
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UNOPROSTONE Usage And Synthesis
Uses
Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent.
Definition
ChEBI: Unoprostone is an oxo monocarboxylic acid, a prostaglandins Falpha and a ketone. It has a role as an antiglaucoma drug and an antihypertensive agent.
General Description
Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF2α analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously.
UNOPROSTONESupplier
BeiJing Hwrk Chemicals Limted
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- 0757-86329057 18934348241
- sales4.gd@hwrkchemical.com
LGM Pharma
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- 1-(800)-881-8210
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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- 18521735133 18521732826;
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Amadis Chemical Company Limited
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- 571-89925085
- sales@amadischem.com
Alchemist-pharm chemical Technology Co. Ltd.
- Tel
- 0371-67991738 13783628208
- carl@alchemist-pharm.com