Basic information Safety Supplier Related

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA

Basic information Safety Supplier Related

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Basic information

Product Name:
CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
Synonyms:
  • 3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid
  • CBZ-AEEA
  • CBZ-AEEA.DCHA
  • CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
  • Cb-NH-PEG2-CH2COOH
  • 2-[2-(Cbz-amino)ethoxy]ethoxyacetic acid
  • 8-Benzyloxycarbonylamino-3,6-dioxaoctanoic acid
  • 3,6,11-Trioxa-9-azadodecanoic acid, 10-oxo-12-phenyl-
CAS:
165454-06-8
MF:
C14H19NO6
MW:
297.3
Mol File:
165454-06-8.mol
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CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Chemical Properties

Boiling point:
506.6±45.0 °C(Predicted)
Density 
1.233±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
3.40±0.10(Predicted)
form 
Viscous Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C14H19NO6/c16-13(17)11-20-9-8-19-7-6-15-14(18)21-10-12-4-2-1-3-5-12/h1-5H,6-11H2,(H,15,18)(H,16,17)
InChIKey
GWUWSVXMAZFFNT-UHFFFAOYSA-N
SMILES
C(O)(=O)COCCOCCNC(=O)OCC1=CC=CC=C1
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CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Usage And Synthesis

Uses

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHASupplier

Suzhou Highfine Biotech Co., Ltd Gold
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0512-69209928 18796809688
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Jia Xing Isenchem Co.,Ltd
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Bide Pharmatech Ltd.
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Shanghai Qiao Chemical Science Co., Ltd
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021-58892003
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