Hh-Ag 1.3
Hh-Ag 1.3 Basic information
- Product Name:
- Hh-Ag 1.3
- Synonyms:
-
- 3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide
- Smoothened Agonist, HCl
- SAG . dihydrochloride (water soluble)
- 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
- Hh-Ag 1.3
- Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-
- Frizzled6 agonist SAG1.3
- CAS:
- 364590-63-6
- MF:
- C28H28ClN3OS
- MW:
- 490.06
- Mol File:
- 364590-63-6.mol
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Hh-Ag 1.3 Chemical Properties
- Boiling point:
- 688.6±55.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- pka
- 10?+-.0.40(Predicted)
- form
- White to off-white solid.
- Water Solubility
- Soluble in water.
- Sensitive
- Light Sensitive & Hygroscopic
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Hh-Ag 1.3 Usage And Synthesis
Uses
Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.
Hh-Ag 1.3Supplier
Shanghai Witofly Chemical Co.,Ltd
- Tel
- sales@witofly.com
ChemStrong Scientific Co.,Ltd
- Tel
- 0755-0755-66853366 13670046396
- sales@chem-strong.com
Finetech Industry Limited
- Tel
- 027-87465837 19945049750
- sales@finetechnology-ind.com
Aikon International Limited
- Tel
- 025-58851090 13611564524
- lwan@aikonchem.com
Nanjing crow LuNing pharmaceutical technology co., LTD
- Tel
- 13382066392