Hh-Ag 1.3

Product Name: Hh-Ag 1.3
CAS No.: 364590-63-6
Chemical Name: Hh-Ag 1.3
Synonyms: Hh-Ag 1.3;Smoothened Agonist, HCl;Frizzled6 agonist SAG1.3;SAG . dihydrochloride (water soluble);3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide;Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
CBNumber: CB72524538
Molecular Formula: C28H28ClN3OS
Formula Weight: 490.06
MOL File: 364590-63-6.mol

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Hh-Ag 1.3 Property

Boiling point:: 688.6±55.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
pka: 10?+-.0.40(Predicted)
form: White to off-white solid.
Water Solubility: Soluble in water.
Sensitive: Light Sensitive & Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 566660
Product name: Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
Packaging: 1mg
Price: $361
Updated: 2024/03/01

Sigma-Aldrich

Product number: 566660
Product name: Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
Packaging: 5mg
Price: $1030
Updated: 2024/03/01

Alfa Aesar

Product number: J64726
Product name: Smoothened Agonist dihydrochloride dihydrate
Packaging: 1mg
Price: $117
Updated: 2021/12/16

Alfa Aesar

Product number: J64726
Product name: Smoothened Agonist dihydrochloride dihydrate
Packaging: 5mg
Price: $415
Updated: 2021/12/16

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Hh-Ag 1.3 Chemical Properties,Usage,Production

Uses

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

Hh-Ag 1.3 Preparation Products And Raw materials

Raw materials

Preparation Products

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Hh-Ag 1.3 Suppliers

China 8 United Kingdom 2 United States 3 Global 13

Shanghai Witofly Chemical Co.,Ltd

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ChemStrong Scientific Co.,Ltd

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Finetech Industry Limited

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Aikon International Limited

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Nanjing crow LuNing pharmaceutical technology co., LTD

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Finetech Industry Limited

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Energy Chemical

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Nantong Hanfang Biotechnology Co. , Ltd.

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Aladdin Scientific

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Country: United States
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364590-63-6, Hh-Ag 1.3Related Search:

JERVINE NVP-LDE225 LDE-225 Diphosphate N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide Purmorphamine

3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide

Smoothened Agonist, HCl

SAG . dihydrochloride (water soluble)

3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride

Hh-Ag 1.3

Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-

Frizzled6 agonist SAG1.3

364590-63-6