BMP-6, HUMAN Chemical Properties

storage temp. 

−20°C

form 

lyophilized powder

biological source

human

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

MSDS

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BMP-6, HUMAN Usage And Synthesis

Biological Activity

Cellular responses to BMP-6 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Mature human and murine BMP-6 demonstrates 96% homology.

Description

BMP6 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 164 amino acids (375-513) and having a molecular mass of 18kDa.
BMP6 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules, which can induce ectopic bone growth. Various BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were initially identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based upon its expression early in embryogenesis, BMP6 has a suggested role in early development. Moreover, the fact that the BMP6 is closely related to BMP5 and BMP7 leads to an assumption of possible bone inductive activity.

BMP-6, HUMAN()Related Product Information

• Intermediate capsid protein VP6
• bone morphogenetic protein 10
• CXCL12/SDF-1
• CCL14/NCC-2
• IL36RN/IL-1F5
• CCL5/RANTES
• CD137/TNFRSF9/4-1BB
• LTA/TNF-beta
• CCL11/Eotaxin
• CD137/TNFRSF9