R-(-)-O-DesMethyl-Venlafaxine-d6 Usage And Synthesis

Biological Activity

(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

References

[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

R-(-)-O-DesMethyl-Venlafaxine-d6(1062609-96-4)Related Product Information

• Venlafaxine
• (5RS)-5-(4-Methoxyphenyl)-3-Methyl-1-oxa-3-azaspiro-[5.5]undecane Hydrochloride
• DesMethoxy Venlafaxine Hydrochloride
• D,L-O-DesMethyl Venlafaxine-d10
• 1-[2-Amino-1-(4-benzyloxyphenyl)-ethyl]-cyclohexanol
• 1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride
• O-DESMETHYL-(RAC-VENLAFAXINE) GLUCURONIDE
• D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine
• N,N-dimethyl-4-methoxyphenylethylamine
• Ethyl α-(p-Methoxyphenyl)-β-(dimethylamino)propionate
• (2RS)-2-Cyclohexyl-2-(4-Methoxyphenyl)-N,NdiMethylethanaMineHydrochloride
• S-(+)-O-DESMETHYL VENLAFAXINE
• O-DesMethyl Venlafaxine Cyclic IMpurity
• Venlafaxine Related Compound A (10 mg) (1-(1-(4-Methoxyphenyl)-2-(methylamino)ethyl)cyclohexanol hydrochloride)
• O-Desmethylvenlafaxine
• D,L N,O-Didesmethylvenlafaxine
• R-(-)-O-DESMETHYLVENLAFAXINE
• (2RS)-2-(Cyclohex-1-enyl)-2-(4-Methoxyphenyl)-N,N-diMethylethanaMine Hydrochloride