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Indacaterol IMrity
Indacaterol IMrity Basic information
- Product Name:
- Indacaterol IMrity
- Synonyms:
-
- Indacaterol IMP
- (S)-Indacaterol
- 2(1H)-Quinolinone, 5-[(1S)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-
- (S)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
- Indoterol impurity 06
- Indatrol Impurity 6
- Indacaterol IMrity
- Indatrol Impurity
- CAS:
- 1235445-80-3
- MF:
- C24H28N2O3
- MW:
- 392.49
- Mol File:
- 1235445-80-3.mol
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Indacaterol IMrity Chemical Properties
- Boiling point:
- 660.3±55.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- pka
- 8.68±0.20(Predicted)
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Indacaterol IMrity Usage And Synthesis
Uses
(S)-Indacaterol is the S-enantiomer of Indacaterol (HY-14299). Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist[1][2].
References
[1] Jadwiga A Wedzicha, et al. Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD. N Engl J Med. 2016 Jun 9;374(23):2222-34. DOI:10.1056/NEJMoa1516385
[2] Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. DOI:10.14348/molcells.2014.0076
Indacaterol IMritySupplier
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