ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > Mcl1-IN-1
Mcl1-IN-1
Mcl1-IN-1 Basic information
- Product Name:
- Mcl1-IN-1
- Synonyms:
-
- CS-1222
- Mcl1-IN-1
- 2-[2-[(5-Chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy]acetic acid
- Mcl1 inhibitor 1
- Acetic acid, 2-[2-[(5-chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy]-
- Mcl1 IN 1,Mcl-1-IN-1,Mcl1IN1
- CAS:
- 713492-66-1
- MF:
- C23H18ClN3O4
- MW:
- 435.86
- Mol File:
- 713492-66-1.mol
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Mcl1-IN-1 Chemical Properties
- Boiling point:
- 681.6±55.0 °C(Predicted)
- Density
- 1.455±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 50 mg/mL (114.72 mM)
- form
- Solid
- pka
- 3.10±0.10(Predicted)
- color
- White to off-white
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Mcl1-IN-1 Usage And Synthesis
Description
Mcl1-IN-1 is a potent and selective inhibitor of the apoptosis regulating proteins Mcl-1.
Uses
Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 μM).
IC 50
Mcl-1: 2.4 μM (IC50)
References
[1] Richard DJ, et al. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9. DOI:10.1016/j.bmc.2013.08.017
Mcl1-IN-1Supplier
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
MedChemexpress LLC
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- 021-58955995
- sales@medchemexpress.cn
SPIRO PHARMA
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- eric_feng1954@126.com
Guangzhou QiYun Biotechnology Co., Ltd.
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- 020-61288194 61288195
- 505721671@qq.com
Tianjin Kailiqi Biotechnology Co., Ltd.
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- 15076683720
- klq@cw-bio.com