3-tert-Butoxycarbonylphenylboronic acid Chemical Properties

Melting point:

96-102°C

Boiling point:

375.0±44.0 °C(Predicted)

Density 

1.15±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

7.72±0.10(Predicted)

color 

White to Almost white

CAS DataBase Reference

220210-56-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-60-37

Hazard Note 

Irritant/Keep Cold

HS Code 

29319000

3-tert-Butoxycarbonylphenylboronic acid Usage And Synthesis

Chemical Properties

White to light yellow crystal powde

Preparation

The 10L glass reactor is equipped with mechanical stirring, thermometer and constant pressure dropping funnel. Under nitrogen protection, add 3 moles of raw material m-carboxybenzene boric acid and 4kg tetrahydrofuran. Add 4.5 moles of thionyl chloride dropwise under reflux and stirring, react for 4 hours, cool to 0-5°C, add 7.5 moles of potassium tert-butoxide in batches, continue stirring for 1 hour after the addition, add 2kg of water, and acidify with acetic acid. Let sit and let the liquid separate. The organic phase was concentrated to obtain a crude product, which was recrystallized by adding 2 kg of petroleum ether to obtain a solid product, 3-tert-Butoxycarbonylphenylboronic acid, with a purity of 98% and a molar yield of 95%.

3-tert-Butoxycarbonylphenylboronic acid(220210-56-0)Related Product Information

• ALUMINUM TERT-BUTOXIDE
• Methyl 4-tert-butylbenzoate
• Tetrabutyl titanate
• tert-Butylbenzene
• tert-Butanol
• Phenylboronic acid
• Lithium tri-tert-butoxyaluminum hydride
• Folic acid
• Citric acid
• Ethyl 2-(Chlorosulfonyl)acetate
• Ascoric Acid
• 3-(PYRROLIDINE-1-CARBONYL)PHENYLBORONIC ACID
• (3-Phenylaminocarbonylphenyl)boronic acid
• [3-(Isobutylaminocarbonyl)phenyl]boronic acid
• [3-(N-Isopropylaminocarbonyl)phenyl]boronic acid
• 3-Nitrophenylboronic acid
• 3-(N,N-DIETHYLAMINOCARBONYL)PHENYLBORONIC ACID
• 3-(BUTYLAMINOCARBONYL)PHENYLBORONIC ACID