ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > Palbociclib-d8
Palbociclib-d8
Palbociclib-d8 Basic information
- Product Name:
- Palbociclib-d8
- Synonyms:
-
- Palbociclib-d8
- PD 0332991-d8
- [2H8]-Palbociclib
- 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
- Palbociclib D8Q: What is Palbociclib D8 Q: What is the CAS Number of Palbociclib D8 Q: What is the storage condition of Palbociclib D8 Q: What are the applications of Palbociclib D8
- 6-acetyl-8-cyclopentyl-5-methyl-2-({5-[(2,2,3,3,5,5,6,6-2H?)piperazin-1-yl]pyridin-2-yl}amino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one
- *Tramadol Impurity 24
- D8-Palbociclib
- CAS:
- 1628752-83-9
- MF:
- C24H21D8N7O2
- MW:
- 455.582054224
- Mol File:
- 1628752-83-9.mol
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Palbociclib-d8 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO: Soluble
- form
- A solid
- color
- Light yellow to yellow
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Palbociclib-d8 Usage And Synthesis
Uses
Palbociclib-d8 is labelled Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
IC 50
Cdk4/cyclin D3: 9 nM (IC50); Cdk4/cyclin D1: 11 nM (IC50); Cdk6/cyclin D2: 16 nM (IC50); DYRK1A: 2000 nM (IC50); MAPK: 8000 nM (IC50)
Palbociclib-d8Supplier
Daicel Chiral Technologies (China)CO.,LTD
- Tel
- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
Bide Pharmatech Ltd.
- Tel
- 400-400-164-7117 18317119277
- product02@bidepharm.com
Artis Biotech Co. Ltd.
- Tel
- 19138486554; 18108108965
- sales@artisbio.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
Chengdu Novel Biomedical Co., Ltd.
- Tel
- 028-85255396 18302801538
- cdnovell@163.com