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Palbociclib-d8

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Palbociclib-d8 Basic information

Product Name:
Palbociclib-d8
Synonyms:
  • Palbociclib-d8
  • PD 0332991-d8
  • [2H8]-Palbociclib
  • 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
  • Palbociclib D8Q: What is Palbociclib D8 Q: What is the CAS Number of Palbociclib D8 Q: What is the storage condition of Palbociclib D8 Q: What are the applications of Palbociclib D8
  • 6-acetyl-8-cyclopentyl-5-methyl-2-({5-[(2,2,3,3,5,5,6,6-2H?)piperazin-1-yl]pyridin-2-yl}amino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • *Tramadol Impurity 24
  • D8-Palbociclib
CAS:
1628752-83-9
MF:
C24H21D8N7O2
MW:
455.582054224
Mol File:
1628752-83-9.mol
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Palbociclib-d8 Chemical Properties

storage temp. 
Store at -20°C
solubility 
DMSO: Soluble
form 
A solid
color 
Light yellow to yellow
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Palbociclib-d8 Usage And Synthesis

Uses

Palbociclib-d8 is labelled Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

IC 50

Cdk4/cyclin D3: 9 nM (IC50); Cdk4/cyclin D1: 11 nM (IC50); Cdk6/cyclin D2: 16 nM (IC50); DYRK1A: 2000 nM (IC50); MAPK: 8000 nM (IC50)

Palbociclib-d8Supplier

Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Email
han_yajun@dctc.daicel.com
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Email
product02@bidepharm.com
Artis Biotech Co. Ltd.
Tel
19138486554; 18108108965
Email
sales@artisbio.com
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Email
2853530910@QQ.com
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Email
cdnovell@163.com
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