Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Basic information
- Product Name:
- Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
- Synonyms:
-
- Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
- 5-HT3 antagonist 2
- 5HT3 antagonist 2,5 HT3 antagonist 2,5-HT-3 antagonist 2
- CAS:
- 128199-93-9
- MF:
- C18H21N3O
- MW:
- 295.39
- Mol File:
- 128199-93-9.mol
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Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Chemical Properties
- Boiling point:
- 490.4±35.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 11.29±0.40(Predicted)
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Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Usage And Synthesis
Uses
5-HT3 antagonist 2 is a 5-HT3 receptor antagonist.
IC 50
5-HT3 Receptor
References
[1] Swain CJ, et al. Novel 5-HT3 antagonists: indol-3-ylspiro(azabicycloalkane-3,5'(4'H)-oxazoles). J Med Chem. 1992 Mar 20;35(6):1019-31. DOI:10.1021/jm00084a007
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