Water-18O Chemical Properties

Melting point:

0 °C(lit.)

Boiling point:

100 °C(lit.)

Density 

1.11 g/mL at 20 °C(lit.)

storage temp. 

Inert atmosphere,Room Temperature

form 

Colourless Liquid

color 

Colorless to light yellow

Stability:

Hygroscopic

InChI

InChI=1S/H2O/h1H2/i1+2

InChIKey

XLYOFNOQVPJJNP-NJFSPNSNSA-N

SMILES

[18OH2]

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

21

HS Code 

28459000

MSDS

• Language:English Provider:SigmaAldrich

Water-18O Usage And Synthesis

Description

Only 0.2% of the oxygen-18O isotope exists in atmospheric oxygen. The Water-18O is manufactured by enriching the oxygen-18O over 98 atom% and is used to produce the [18F]FDG *1 PET diagnostic reagent for cancer. Water enriched in the oxygen-18 isotope (Water-18O) is widely used in medicine, agrochemistry and biochemistry. Oxygen-18 was first enriched to 99.5% in 1943 using thermal diffusion. To date, the use of electrolysis, chemical isotope exchange, gas diffusion, and rectification of oxygen, nitric oxide, and water has been described to enrich water with oxygen-18. Among them, the method of rectification of water, first demonstrated in 1944, is successfully used now in industry.

Chemical Properties

Colourless Liquid

Uses

Water-18O, 97 atom % 18O is used in DNA stable isotope probing (SIP) to investigate microbial growth and death in environmental samples.

Uses

Water-¹⁸O is an isotopically modified water, which is appropriate for PET applications.
It can also be used:

• In paleoclimatology, hydrology, and plant ecology to determine soil stable oxygen isotope analysis of plant cellulose using δ¹⁸O.
• To determine the diffusion of moisture into crystals using secondary ion mass spectrometry (SIMS).

Definition

ChEBI: A form of water consisting of two hydrogen atoms covalently bonded to an oxygen-18 atom.

Water-18O(14314-42-2)Related Product Information

• Oxygen
• DEUTERIUM OXIDE
• Sodium alkylbenzene sulfonate
• Pyridinium dichromate
• P-DIAZOBENZENESULFONIC ACID
• TSP
• Barite
• METHANOL-18O
• Oxygen-18O2
• SODIUM ACETATE-18O2
• L-Leucine-18O2
• Urea-18O
• DEUTERIUM OXIDE-18O
• NITRIC-15N OXIDE-18O
• CARBON DIOXIDE (18O2)
• CARBON MONOXIDE (18O)
• CARBON MONOXIDE (13C; 18O)
• Heavy-oxygen water