Basic information Safety Supplier Related

Tropifexor

Basic information Safety Supplier Related

Tropifexor Basic information

Product Name:
Tropifexor
Synonyms:
  • LJN 452;LJN-452;LJN452
  • CS-2712
  • CPD1549
  • Tropifexor
  • Tropifexor (LJN452)
  • LJN452
  • LJN452,Tropifexor
  • 2-[(1R,3r,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
CAS:
1383816-29-2
MF:
C29H25F4N3O5S
MW:
603.58
Product Categories:
  • API
Mol File:
1383816-29-2.mol
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Tropifexor Chemical Properties

Boiling point:
700.0±65.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:80.66(Max Conc. mg/mL);133.64(Max Conc. mM)
form 
A crystalline solid
pka
3.84±0.10(Predicted)
color 
Off-white to yellow
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Tropifexor Usage And Synthesis

Uses

Tropifexor, is a highly potent non-bile acid FXR agonist for the treatment of cholestatic liver diseases and nonalcoholic steatohepatitis (NASH).

TropifexorSupplier

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