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Cytidine 5'-diphosphate trisodium salt

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Cytidine 5'-diphosphate trisodium salt Basic information

Product Name:
Cytidine 5'-diphosphate trisodium salt
Synonyms:
  • -diphosphate(CDP),sodium salt,hydrate
  • Cytidine 5'-(trihydrogen diphosphate), trisodium salt (9CI)
  • 5'-CDPNa3
  • Cytidine-5'-diphosphate trisodiuM salt, 99+%
  • Cytidine 5'-(Trihydrogen Diphosphate) TrisodiuM Salt Hydrate
  • Cytidine 5'-(Trihydrogen Pyrophosphate) TrisodiuM Salt Hydrate
  • TrisodiuM Cytidine 5'-Diphosphate Hydrate
  • 5'-CDP 3Na Hydrate
CAS:
34393-59-4
MF:
C9H16N3NaO11P2
MW:
427.17
EINECS:
251-990-8
Product Categories:
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • Phosphorylating and Phosphitylating Agents
  • Material
  • Biochemistry
  • Nucleosides, Nucleotides & Related Reagents
  • Nucleotides and their analogs
  • Amino Acids
  • Pharmaceutical Intermediates
  • Pharmaceutical
Mol File:
34393-59-4.mol
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Cytidine 5'-diphosphate trisodium salt Chemical Properties

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form 
Crystalline Powder
color 
White
biological source
yeast
Water Solubility 
Freely soluble in water, insoluble in ethanol, chloroform and ether.
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-37/39-36-26
WGK Germany 
3
1-10
HS Code 
29349990
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Cytidine 5'-diphosphate trisodium salt Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

Cytidine 5'-Diphosphate trisodium salt (5'-CDPNa3) is a diphosphate nucleoside derived from Cytidine. An inhibitor of glycogenin-catalyzed glucosyl and xylosyl transfer It is used as a therapeutic agent in treatment prevention of myocardial isc hemia accompanied with cerebral ischemia.

Application

Cytidine 5′-diphosphate sodium salt (5'-CDPNa3) has been used:

  • as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections
  • in ribonucleotide reductase assay
  • dCDP formation assay.

General Description

Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK). CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis.

Biochem/physiol Actions

Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.

in vivo

CDP-ribitol can be used for the Diagnostics and research of CDP-l-ribitol pyrophosphorylase A (CRPPA) muscular dystrophy[3].

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