MILBEMECTIN A4
MILBEMECTIN A4 Basic information
- Product Name:
- MILBEMECTIN A4
- Synonyms:
-
- milbemycinb-1
- MILBEMECTIN A4
- milbemectine a4
- milbemycin A4
- (25R)-25-Ethyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B
- (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B
- Antibiotic B-41A4
- Milbemycin α3
- CAS:
- 51596-11-3
- MF:
- C32H46O7
- MW:
- 542.7
- Mol File:
- 51596-11-3.mol
MILBEMECTIN A4 Chemical Properties
- Melting point:
- 212-215°
- alpha
- D20 +106° (c = 0.25 in acetone)
- Boiling point:
- 732.9±60.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
- storage temp.
- 0-6°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- A solid
- pka
- 12.46±0.70(Predicted)
- color
- White to off-white
- EPA Substance Registry System
- Milbemycin A4 (51596-11-3)
MILBEMECTIN A4 Usage And Synthesis
Description
Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.
Uses
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.
Uses
Milbemycin A4 is a macrolide compound that is a member of a complex family of macrocyclic lactones that contain structural group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. Antibacterial and insecticide (1,2). It potentiates glutamate and GABA-gated chloride-channel opening. Used in the synthesis of Milbemycin A17 (3).
Uses
Acaricide.
Definition
ChEBI: Milbemycin A4 is a milbemycin.
MILBEMECTIN A4Supplier
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MILBEMECTIN A4(51596-11-3)Related Product Information
- MilbeMycin A3 OxiMe
- MilbeMycin A4 OxiMe
- Miconazole IMpurity I
- Miconazole IMpurity B
- MILRINONE RELATED COMPOUND A (50 MG) (1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CAR-BOXAMIDE)
- 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxylic acid
- 1,6-Dihydro-2-(hydroxyMethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile
- Milbemycin oxime
- Isoconazole
- Milbemycin EP Impurity D
- Milrinone Impurity 13
- Miconazole Impurity
- 5-Decyano 5-(Ethyl Formate) Milrinone
- Milrinone Impurity 17
- Milrinone Impurity 14
- Milbemycin EP Impurity E
- Miconazole EP Impurity E
- MILBEMECTIN A3