Br-PEG7-OH
Br-PEG7-OH Basic information
- Product Name:
- Br-PEG7-OH
- Synonyms:
-
- Br-PEG7-OH
- 20-Bromo-3,6,9,12,15,18-hexaoxaicosan-1-ol
- Br-PEG7-OH/3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-bromo-
- 3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-bromo-
- 2-[2-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- CAS:
- 86220-35-1
- MF:
- C14H29BrO7
- MW:
- 389.28
- Mol File:
- 86220-35-1.mol
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Br-PEG7-OH Chemical Properties
- Boiling point:
- 443.0±40.0 °C(Predicted)
- Density
- 1.261±0.06 g/cm3(Predicted)
- form
- Liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to light yellow
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Br-PEG7-OH Usage And Synthesis
Biological Activity
Bromo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Br-PEG7-OHSupplier
Borenpharm Co., Ltd
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Zhengzhou Alfa Chemical Co.,Ltd
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