Br-PEG7-Br
Br-PEG7-Br Basic information
- Product Name:
- Br-PEG7-Br
- Synonyms:
-
- Br-PEG7-Br
- Bromo-PEG8-bromide
- CAS_177987-04-1
- Br-PEG7-CH2CH2Br
- 3,6,9,12,15,18,21-Heptaoxatricosane, 1,23-dibromo-
- 1,23-dibromo-3,6,9,12,15,18,21-heptaoxatricosane
- Br PEG7 Br,PROTAC Linkers,inhibit,Br-PEG-7-Br,BrPEG7Br,Inhibitor
- Br-PEG7-CH2CH2Br/3,6,9,12,15,18,21-Heptaoxatricosane, 1,23-dibromo-
- CAS:
- 177987-04-1
- MF:
- C16H32Br2O7
- MW:
- 496.23
- Mol File:
- 177987-04-1.mol
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Br-PEG7-Br Chemical Properties
- Boiling point:
- 486.9±40.0 °C(Predicted)
- Density
- 1.364±0.06 g/cm3(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
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Br-PEG7-Br Usage And Synthesis
Biological Activity
Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Br-PEG7-BrSupplier
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