Basic information Safety Supplier Related

11-DEHYDROCORTICOSTERONE

Basic information Safety Supplier Related

11-DEHYDROCORTICOSTERONE Basic information

Product Name:
11-DEHYDROCORTICOSTERONE
Synonyms:
  • 11-dehydrocorticosterone crystalline
  • 21-hydroxypregn-4-ene-3,11,20-trione
  • 4-Pregene-21-ol-3,11,20-trione
  • 17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
  • 11-Oxocorticosterone
  • NSC-9702
  • 17-(2-hydroxyethanoyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
  • 17-glycoloyl-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-quinone
CAS:
72-23-1
MF:
C21H28O4
MW:
344.44
EINECS:
200-776-2
Mol File:
72-23-1.mol
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11-DEHYDROCORTICOSTERONE Chemical Properties

Melting point:
183.5°C
Boiling point:
399.53°C (rough estimate)
Density 
1.0556 (rough estimate)
refractive index 
1.4430 (estimate)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Dioxane (Slightly), Methanol (Slightly)
form 
Solid
pka
12.95±0.10(Predicted)
color 
White to Pale Yellow
optical activity
+34725 (c 0.23, C6H6)
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11-DEHYDROCORTICOSTERONE Usage And Synthesis

Uses

11-Dehydrocorticosterone is a precursor to corticosterone (C695700), converted by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) which plays a role in glucocorticoid-induced insulin resistance.

Definition

ChEBI: An 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidised to give the corresponding ketone.

11-DEHYDROCORTICOSTERONESupplier

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