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2-Acetamido-4-methylphenol

Basic information Safety Supplier Related

2-Acetamido-4-methylphenol Basic information

Product Name:
2-Acetamido-4-methylphenol
Synonyms:
  • n-(2-hydroxy-5-methylphenyl)-acetamid
  • N-(2-Hydroxy-5-methylphenyl)acetamide
  • N1-(2-HYDROXY-5-METHYLPHENYL)ACETAMIDE
  • 2-ACETOMIDO-P-CRESOL
  • 2-ACETAMIDO-4-METHYLPHENOL
  • 2-HYDROXY-5-METHYLACETANILIDE
  • 2-acetamido-4-cresol
  • 2-Acetylamino-4-methylphenol
CAS:
6375-17-3
MF:
C9H11NO2
MW:
165.19
EINECS:
228-934-6
Product Categories:
  • Intermediates of Dyes and Pigments
  • Phenol&Thiophenol&Mercaptan
Mol File:
6375-17-3.mol
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2-Acetamido-4-methylphenol Chemical Properties

Melting point:
151 °C
Boiling point:
336.5±30.0 °C(Predicted)
Density 
1.203±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
9.57±0.48(Predicted)
color 
White to Light yellow
CAS DataBase Reference
6375-17-3(CAS DataBase Reference)
EPA Substance Registry System
2'-Hydroxy-5'-methylacetanilide (6375-17-3)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
TSCA 
Yes
HS Code 
2924.29.7790

MSDS

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2-Acetamido-4-methylphenol Usage And Synthesis

Chemical Properties

needles

General Description

Solid.

Reactivity Profile

Compounds in this group do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Many of them form metal salts that tend toward detonation by rather mild shock. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Fire Hazard

Flash point data for 2-Acetamido-4-methylphenol are not available. 2-Acetamido-4-methylphenol is probably combustible.

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