4-METHOXY-3-BUTEN-2-ONE Chemical Properties

Melting point:

0℃

Boiling point:

200 °C (lit.)

Density 

0.982 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.468(lit.)

Flash point:

146 °F

storage temp. 

2-8°C

solubility 

sol THF, ether, acetonitrile, benzene.

form 

liquid

Appearance

Colorless to light yellow Liquid

BRN 

2070991

InChI

InChI=1S/C5H8O2/c1-5(6)3-4-7-2/h3-4H,1-2H3/b4-3+

InChIKey

VLLHEPHWWIDUSS-ONEGZZNKSA-N

SMILES

CC(=O)/C=C/OC

Safety Information

Risk Statements 

10

Safety Statements 

23-24/25

RIDADR 

1224

WGK Germany 

3

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-METHOXY-3-BUTEN-2-ONE Usage And Synthesis

Uses

4-Methoxy-3-buten-2-one is a versatile four-carbon synthon; precursor to the Danishefsky diene; Diels-Alder dienophile; dipolarophile; electrophilic four-carbon synthon subject to conjugate addition at C-4 followed by elimination of the methoxide anion; its enolate is a nucleophilic four-carbon building block.

storage

4-Methoxy-3-buten-2-one may be harmful by inhalation, ingestion, or skin absorption; may cause skin and eye irritation; in addition to standard safety practice, mechanical exhaust is required. Do not breathe vapor. Store in refrigerator under nitrogen or argon.

4-METHOXY-3-BUTEN-2-ONE(51731-17-0)Related Product Information

• trans-4-Methycyclohexyl isocyanate
• p-Coumaric acid
• TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID
• trans-4-Methylcyclohexyl amine
• trans-4-MethoxycyclohexanaMine HCl
• trans-Methyl4-hydroxycyclohexanecarboxylate
• trans-4-Methylcyclohexylamine hydrochloride
• 3-Methoxy-3-buten-2-one
• 4-METHOXY-3-BUTEN-2-ONE
• 4-(Dimethylamino)-4-methoxy-3-buten-2-one