COMPOUND 52
COMPOUND 52 Basic information
- Product Name:
- COMPOUND 52
- Synonyms:
-
- NG-52
- 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLORANILINO)-9-ISOPROPYLPURINE
- 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE
- COMPOUND 52
- 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine, NG-52
- 2-((6-((3-chlorophenyl)aMino)-9-isopropyl-9H-purin-2-yl)aMino)ethanol
- 2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]ethanol
- NG 52 (Compound 52 )
- CAS:
- 212779-48-1
- MF:
- C16H19ClN6O
- MW:
- 346.81
- Product Categories:
-
- Inhibitors
- Mol File:
- Mol File
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COMPOUND 52 Chemical Properties
- Boiling point:
- 587.7±60.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- methylene chloride: 50 mg/mL, clear, colorless
- form
- powder
- pka
- 14.54±0.10(Predicted)
- color
- white to off-white
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MSDS
- Language:English Provider:SigmaAldrich
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COMPOUND 52 Usage And Synthesis
Description
NG 52 is a tri-substituted purine that binds to the ATP-binding site of yeast cyclin-dependent kinases, inhibiting Cdc28p and Pho85p (IC50s = 7 and 2 μM, respectively). It is ineffective against the yeast kinases Kin28p, Srb10, and Cak1p. NG 52 is cell permeable and inhibits the growth of S. cerevisiae (GI50 = 30 μM). It is an analog of purvalanol A , a potent inhibitor of mammalian cyclin-dependent kinases.
COMPOUND 52Supplier
Syntechem Co.,Ltd
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Haoyuan Chemexpress Co., Ltd.
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MedChemexpress LLC
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Shanghai JiYi Biotechnology Co. Ltd.
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