GATA2 Antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Mouse;Rat

Background

The zinc finger transcription factor GATA-2 is widely expressed and plays an essential role in many developmental processes. Studies on GATA-2 knockout mice indicate that this protein is required in hematopoiesis. GATA-2 also inhibits the differentiation of white and brown adipocytes and has been shown to suppress the proliferation of neuronal progenitor cells.

References

[1] Tong, Q. et al. (2003) Drug News Perspect. 16, 585-588.
[2] Tsai, F.Y. et al. (1994) Nature 371, 221-226.
[3] Tong, Q. et al. (2005) Mol. Cell. Biol. 25, 706-715.
[4] Tsai, J. et al. (2005) EMBO Rep. 6, 879-884.
[5] El Wakil, A. et al. (2006) Development 133, 2155-2165.

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