GCK antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

Germinal center kinase is the founding member of the GCK family, a group of serine/threonine kinases homologous to the yeast Ste20 kinase. GCK is activated by TNF and associated with TRAF2 and MEKK1, thereby activating the SAPK/JNK pathway. GCK does not significantly phosphorylate MEKK1, instead it enhances MEKK1 oligomerization and autophosphorylation. GCK binds and activates MLK3, indicating that GCK may have other effectors.

References

[1] Pombo, C. M. et al. (1995) Nature 377, 750-754.
[2] Yuasa, T. et al. (1998) J. Biol. Chem. 273, 22681-22692.
[3] Chadee, D. N. et al. (2002) Mol. Cell. Biol. 22, 737-749.

GCK antibody()Related Product Information

• SLC2A4 antibody
• MYL9 antibody
• SLC2A2 Antibody
• GRK2 antibody
• AGO4 Antibody
• MYB antibody
• LPAR3 Antibody
• Anti-CD24
• HINT3 ANTIBODY
• PFN1 Antibody