Ub-ACC Usage And Synthesis

Uses

Ubiquitin-ACC is a fluorogenic substrate for a wide range of deubiquitinating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin specific proteases (USPs). It is a particularly useful reagent for the study of deubiquitinating activity where detection sensitivity or continuous monitoring of activity is essential. 

DUB assays using UCH-L3, OTUD2 and USP30 demonstrated that Ub-ACC shows nearly 2-fold higher sensitivity than Ub-AMC.

Ub-ACC()Related Product Information

• K27-Diubiquitin
• K11-Diubiquitin
• K63-Diubiquitin
• K6-Diubiquitin
• UB-AMC
• K33-Diubiquitin
• K48-Diubiquitin
• Met1-Diubiquitin
• K29-Diubiquitin