Glycochenodeoxycholic acid sodium salt Chemical Properties

Melting point:

160-170 °C

storage temp. 

room temp

solubility 

H₂O: 50 mg/mL, clear, faintly yellow

form 

Solid

color 

White to Pale Brown

BRN 

3847290

Stability:

Hygroscopic

InChI

InChI=1/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-;/s3

InChIKey

AAYACJGHNRIFCT-YQIULKNUNA-M

SMILES

[C@@]12([H])CC[C@H]([C@H](C)CCC(=O)NCC([O-])=O)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@@H](O)C[C@@]3([H])C[C@@H](O)[C@@]21[H].[Na+] |&1:0,4,5,16,20,22,26,29,32,34,r|

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

3-10

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich

Glycochenodeoxycholic acid sodium salt Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

Glycochenodeoxycholic Acid Sodium Salt is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

Uses

Sodium glycochenodeoxycholate has been used in a study to assess the repair of DNA damage induced by bile salts. It has also been used in a study to investigate enterotoxin production by Clostridium perfringens type A in the presence of human bile salts.

Definition

ChEBI: A bile acid salt that is the sodium salt of glycochenodeoxycholic acid.

Purification Methods

Dissolve it in EtOH, filter it and concentrate it to crystallisation, and recrystallise from a little EtOH. It also recrystallises from EtOH/Et2O. [Beilstein 10 IV 1611.]

Glycochenodeoxycholic acid sodium salt(16564-43-5)Related Product Information

• Glycochenodeoxycholic Acid
• Glycochenodeoxycholic Acid-3-O-β-glucuronide Disodium Salt
• Glycochenodeoxycholic Acid 3-Sulfate DisodiuM Salt
• Glycine tert butyl ester hydrochloride
• Glycine ethyl ester hydrochloride
• Glycine methyl ester hydrochloride
• Glycinamide
• (3a,5b,7a)-24-[(carboxymethyl)amino]-7-hydroxy-24-oxocholan-3-yl b-D-glucopyranosiduronic acid
• SODIUM GLYCOCHOLATE HYDRATE, 98
• Sodium deoxycholate
• Sodium cholate
• Glycocholic acid
• GLYCOCHOLIC ACID SODIUM SALT
• Chenodeoxycholic acid
• CHENODEOXYCHOLIC ACID SODIUM
• Sodium tauroglycocholate
• Cholic acid
• SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
• Sodium Glycochenodeoxycholate