3-Cyano-6-methyl-2(1H)-pyridinone Chemical Properties

Melting point:

293-295 °C (lit.)

Boiling point:

247.23°C (rough estimate)

Density 

1.2296 (rough estimate)

refractive index 

1.5880 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

9.03±0.10(Predicted)

color 

White to Pale Yellow

Water Solubility 

2.38 g/L (20 ºC)

BRN 

120412

CAS DataBase Reference

4241-27-4(CAS DataBase Reference)

EPA Substance Registry System

3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-2-oxo- (4241-27-4)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-20/21/22

Safety Statements 

36/37/39-26-22-36

RIDADR 

3276

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

PackingGroup 

III

HS Code 

2933399990

MSDS

• Language:English Provider:3-Cyano-2-hydroxy-6-methylpyridine
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Cyano-6-methyl-2(1H)-pyridinone Usage And Synthesis

Chemical Properties

SLIGHTLY YELLOW GRANULAR CRYSTALLINE POWDER

Uses

3-Cyano-6-methyl-2(1H)-pyridinone is a reactant used in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. 3-It has also been used in the preparation of the N3?-pyridyl thiamine, a potent in vitro thiamine antagonist.

General Description

Supramolecular structures of coordination copper(I) compounds of 3-cyano-6-methyl-2(1H)-pyridinone has been investigated.

3-Cyano-6-methyl-2(1H)-pyridinone(4241-27-4)Related Product Information

• 2-Chloro-3-cyanopyridine
• Methyl acetate
• 3-Cyanopyridine
• 2-Chloro-5-chloromethylpyridine
• Kresoxim-methyl
• Thiophanate-methyl
• Bensulfuron methyl
• 2,4,6-Collidine
• Trimethylsilyl cyanide
• CHLOROPHOSPHONAZO III
• Methylparaben
• 4-Methylpyridine
• Methyl acrylate
• 2,6-Lutidine
• Azamethiphos
• METSULFURON METHYL
• Methyl
• Methyl bromide