(R)-2-THIENYLGLYCINE Chemical Properties

Boiling point:

311.8±32.0 °C(Predicted)

Density 

1.418±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

pka

1.88±0.10(Predicted)

Safety Information

WGK Germany 

3

HS Code 

2934999090

MSDS

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(R)-2-THIENYLGLYCINE Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

(R)-2-Thienylglycine is a compound used in the one-pot regioselective synthesis of substituted arylglycines for kinetic resolution by penicillin G acylase.

Purification Methods

Recrystallise 2-(2-thienyl)glycine by dissolving it in H2O (1g in 3 mL), adjusting the pH to 5.5 with aqueous NH3, diluting with MeOH (20 mL), stirring, adjusting the pH to 5.5 and cooling to 0o. Also recrystallise it from small volumes of H2O. [R-isomer: Nishimura et al. Nippon Kagaku Zasshi 82 1688 1961, S-isomer: Johnson & Panetta Chem Abstr 63 14869 1965, Johnson & Hardcastle Chem Abstr 66 10930 1967, RS-isomer: LiBassi et al. Gazz Chim Ital 107 253 1977.] The (±) N-acetyl derivative has m 191o (from H2O) [Schouteenten et al. Bull Soc Chim Fr II 248, II 252 1978].

(R)-2-THIENYLGLYCINE(65058-23-3)Related Product Information

• AMINO-THIOPHEN-2-YL-ACETIC ACID
• 2-Thiopheneacetic acid
• (S)-3-THIENYLGLYCINE
• FMOC-(S)-2-THIENYLGLYCINE
• BOC-(S)-2-THIENYLGLYCINE
• (S)-2-THIENYLGLYCINE,(R)-2-THIENYLGLYCINE,D-2-THIENYLGLYCINE
• BOC-(R)-3-THIENYLGLYCINE
• FMOC-(S)-3-THIENYLGLYCINE
• N-T-BUTOXYCARBONYL-DL-2-THIENYLGLYCINE
• BOC-(R)-2-THIENYLGLYCINE
• (R)-3-THIENYLGLYCINE
• FMOC-(R)-3-THIENYLGLYCINE
• FMOC-(R)-2-THIENYLGLYCINE
• BOC-(S)-3-THIENYLGLYCINE
• N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA-3-THIENYLGLYCINE
• N-3-thienylglycine
• (-)-2-thienylglycine