6,6-DIBENZYL-14-CROWN-4 Chemical Properties

Melting point:

97～103℃

Boiling point:

524.3±35.0 °C(Predicted)

Density 

1.046±0.06 g/cm3(Predicted)

form 

solid

BRN 

5991129

Safety Information

WGK Germany 

3

F 

10

MSDS

• Language:English Provider:SigmaAldrich

6,6-DIBENZYL-14-CROWN-4 Usage And Synthesis

Uses

Dibenzyl-14-crown-4 (6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane) is a crown ether derivate, which serves as neutral carrier in PVC ion-selective electrode, improves the Li+ selectivity against Na+ and K+[1].

Purification Methods

Dissolve it in CHCl3, wash this with saturated aqueous NaCl, dry (MgSO4), evaporate and purify it by chromatography on silica gel and gradient elution with *C6H6/MeOH followed by preparative reverse phase HPLC on an octadecyl silanised silica (ODS) column and eluting with MeOH. It can be recrystallised from MeOH (max 1120 cm-1, C-O-C in KBr). [Kimura et al. Anal Chem 59 2331 1987, see also Maruyama et al. J Chem Soc Perkin Trans 1 2069 1986 and Tsukube et al. J Chem Soc Perkin Trans 1 1033 1986.] It complexes selectively with Li ions.

References

[1] Kimura K, et al., Lithium ion selective electrodes based on crown ethers for serum lithium assay. Anal Chem. 1987 Oct 1;59(19):2331-4. DOI:10.1021/ac00146a004

6,6-DIBENZYL-14-CROWN-4(106868-21-7)Related Product Information

• NEOPENTYLBENZENE
• 2,2-Dibenzyl-1,3-propanediol
• 6,6-DIBENZYL-14-CROWN-4