2,4-Dichloroaniline Chemical Properties

Melting point:

59-62 °C (lit.) 60-65 °C

Boiling point:

245 °C (lit.)

Density 

1.567

vapor pressure 

1hPa at 78℃

refractive index 

1.6000 (estimate)

Flash point:

115°C

storage temp. 

0-6°C

solubility 

methanol: soluble, clear, very faintly brownish-yellow

pka

2.05(at 22℃)

form 

Crystalline Powder

Specific Gravity

1.567 (20℃)

color 

White to beige

Water Solubility 

Insoluble, <0.1 g/100 mL at 23 ºC

BRN 

386422

LogP

2.78 at 20℃

CAS DataBase Reference

554-00-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2,4-dichloro-(554-00-7)

EPA Substance Registry System

2,4-Dichloroaniline (554-00-7)

Safety Information

Hazard Codes 

T,N,Xi

Risk Statements 

23/24/25-33-50/53

Safety Statements 

28-36/37-45-60-61-28A

RIDADR 

UN 3442 6.1/PG 2

WGK Germany 

3

RTECS 

BX2600000

F 

8-9-23

Hazard Note 

Toxic/Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29214210

Hazardous Substances Data

554-00-7(Hazardous Substances Data)

MSDS

• Language:English Provider:2,4-Dichlorobenzenamine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,4-Dichloroaniline Usage And Synthesis

Chemical Properties

pale grey or beige-brown to red-brown crystalline. Melting point 63°C, boiling point 245°C, relative density 1.567 (20/4°C), soluble in organic solvents such as ethanol, ether and acids. Slightly soluble in water. The color will be darkened in air.

Uses

2,4-Dichloroaniline is used as an intermediate in the synthesis of dyestuffs, pigments, and pesticides.

Uses

2,4-Dichloroaniline may be used as an analytical reference standard for the determination of the analyte in water samples by ultrasound-assisted ionic liquid dispersive liquid-phase micro-extraction, capillary electrophoresis with electrochemical and fluorescence detection and gas chromatography-mass spectrometry (GC-MS), respectively.

Uses

2,4-Dichloroaniline is used as a raw material for the synthesis of anti-infective drug ciprofloxacin, pesticide fungicide Imibenconazole, herbicide (PUMA) and dyes.

Preparation

2,4-Dichloroaniline is synthesized from acetanilide by chlorination and hydrolysis.

Definition

ChEBI: 2,4-dichloroaniline is a dichloroaniline carrying chloro substituents at positions 2 and 4.

General Description

Beige crystals.

Air & Water Reactions

2,4-Dichloroaniline may be sensitive to exposure to air. Insoluble in water.

Reactivity Profile

2,4-Dichloroaniline is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,4-Dichloroaniline are not available. 2,4-Dichloroaniline is probably combustible.

2,4-Dichloroaniline(554-00-7)Related Product Information

• 4-Chloroaniline
• 3-Chloroaniline
• 2-Chloroaniline
• 2-[3-[Bis(2-chloroethyl)aMino]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
• Trazodone-D6 Hydrochloride
• 2,6-Dichloropyridine
• Isotrazodone
• Piperazine, 1-(3-broMopropyl)-4-(3-chlorophenyl)-
• Trazodone Hydrochloride BP Impurity H DiHCl
• Trazodone
• 4-chloropyridine
• 4-Hydroxytrazodone
• BIUREA
• 1-(4-Chlorophenyl)-4-(3-chloropropyl)piperazine
• 1-(3-Chlorophenyl)piperazine-d8
• 1-(3-Bromophenyl)piperazine
• MYRISTIC ACID DIETHANOLAMIDE
• 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-7,8-dihydro-7,8-dihydroxy-