REBECCAMYCIN
REBECCAMYCIN Basic information
- Product Name:
- REBECCAMYCIN
- Synonyms:
-
- 5h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6h)-dione,1,11-dichloro-12,13-dihy
- dro-12-(4-o-methyl-beta-d-glucopyranosyl)-
- REBECCAMYCIN
- REBECCAMYCIN, SACCHAROTHRIX AEROCOLONIGENES
- 1,11-Dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione
- NSC 359079
- 7,10-Dichloro-8-(3,4-dihydroxy-6-(hydroxymethyl)-5-methoxytetrahydro-2H-pyran-2-yl)-8,9-dihydro-1H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione
- 5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-
- CAS:
- 93908-02-2
- MF:
- C27H21Cl2N3O7
- MW:
- 570.38
- Mol File:
- 93908-02-2.mol
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REBECCAMYCIN Chemical Properties
- storage temp.
- −20°C
- solubility
- DMSO: ≥3 mg/mL
- form
- solid
- color
- yellow
MSDS
- Language:English Provider:SigmaAldrich
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REBECCAMYCIN Usage And Synthesis
Uses
Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumour activity against several cell lines. Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II. Analogues of rebecamycin have beend tested in clinical trials for cancer therapy.
Uses
Rebeccamycin is a novel indolocarbazole topoisomerase I inhibitor.
Definition
ChEBI: An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens.
storage
+4°C
REBECCAMYCINSupplier
Shanghai Tauto Biotech Co., Ltd.
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- 021-51320588
- tauto@tautobiotech.com
Guangzhou Isun Pharmaceutical Co., Ltd
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- 020-39119399 18927568969
- isunpharm@qq.com
ChemStrong Scientific Co.,Ltd
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- 0755-0755-66853366 13670046396
- sales@chem-strong.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com