Basic information Safety Supplier Related

REBECCAMYCIN

Basic information Safety Supplier Related

REBECCAMYCIN Basic information

Product Name:
REBECCAMYCIN
Synonyms:
  • 5h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6h)-dione,1,11-dichloro-12,13-dihy
  • dro-12-(4-o-methyl-beta-d-glucopyranosyl)-
  • REBECCAMYCIN
  • REBECCAMYCIN, SACCHAROTHRIX AEROCOLONIGENES
  • 1,11-Dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione
  • NSC 359079
  • 7,10-Dichloro-8-(3,4-dihydroxy-6-(hydroxymethyl)-5-methoxytetrahydro-2H-pyran-2-yl)-8,9-dihydro-1H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione
  • 5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-
CAS:
93908-02-2
MF:
C27H21Cl2N3O7
MW:
570.38
Mol File:
93908-02-2.mol
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REBECCAMYCIN Chemical Properties

storage temp. 
−20°C
solubility 
DMSO: ≥3 mg/mL
form 
solid
color 
yellow
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Safety Information

WGK Germany 
-

MSDS

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REBECCAMYCIN Usage And Synthesis

Uses

Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumour activity against several cell lines. Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II. Analogues of rebecamycin have beend tested in clinical trials for cancer therapy.

Uses

Rebeccamycin is a novel indolocarbazole topoisomerase I inhibitor.

Definition

ChEBI: An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens.

storage

+4°C

REBECCAMYCINSupplier

Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Email
isunpharm@qq.com
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Email
sales@chem-strong.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Email
psaitong@jm-bio.com