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Pizotifen Malate

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Pizotifen Malate Basic information

Product Name:
Pizotifen Malate
Synonyms:
  • sandomygranmalate
  • sanomtgran
  • 4-(9,10-DIHYDRO-1-THIA-BENZO[F]AZULEN-4-YLIDENE)-1-METHYL-PIPERIDINE, COMPOUND WITH 2-HYDROXY-SUCCINIC ACID
  • PIZOTYLINE MALATE
  • PIZOTIFEN MALATE
  • 9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene malate (1:1)
  • malic acid, compound with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine (1:1)
  • Einecs 225-970-4
CAS:
5189-11-7
MF:
C23H27NO5S
MW:
429.53
EINECS:
225-970-4
Product Categories:
  • Active Pharmaceutical Ingredients
  • Sandomigran, pizotyline
  • API
Mol File:
5189-11-7.mol
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Pizotifen Malate Chemical Properties

Melting point:
185-186° (dec)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Aqueous Acid (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
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Pizotifen Malate Usage And Synthesis

Uses

Antimigraine

Uses

Pizotifen, C19H21NS· C4H6O5, is piperidine derivatives. Though antihistamines, it is mainly used because of their antiserotonergic properties.

Uses

Pizotifen Malate is an anti migraine drug.

Definition

ChEBI: A malate salt resulting from the reaction of equimolar amounts of pizotifen and malic acid. A sedating antihistamine with strong serotonin antagonist and weak antimuscarinic activity, it is used for the treatment of migraine and the prevention of headache ttacks during cluster periods.

Pizotifen MalateSupplier

Wuhan Jiakai Long Technology Development Co., Ltd.
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