Basic information Safety Supplier Related

TEMAZEPAM-D5

Basic information Safety Supplier Related

TEMAZEPAM-D5 Basic information

Product Name:
TEMAZEPAM-D5
Synonyms:
  • TEMAZEPAM-D5
  • 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-(phenyl-d5)-
  • TEMAZEPAM-D5,100/MLINMETHANOL
  • Temazepam-d5 solution
  • Temazepam-d5 (CRM)
  • 7-chloro-3-hydroxy-1-methyl-5-(2,3,4,5,6-pentadeuteriophenyl)-3H-1,4-benzodiazepin-2-one
  • Temazepam-d5 (phenyl-d5)
  • [2H5]-Temazepam, racemic mixture
CAS:
136765-51-0
MF:
C16H8ClD5N2O2
MW:
305.77
EINECS:
803-032-0
Mol File:
136765-51-0.mol
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TEMAZEPAM-D5 Chemical Properties

Flash point:
9℃
storage temp. 
-20°C
InChIKey
SEQDDYPDSLOBDC-VIQYUKPQSA-N
EPA Substance Registry System
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-(phenyl-d5)- (136765-51-0)
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
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TEMAZEPAM-D5 Usage And Synthesis

Description

Temazepam-d5 (Item No. 15859) is an analytical reference material intended for use as an internal standard for the quantification of temazepam . Temazepam is categorized as a benzodiazepine. Temazepam has sedative-hypnotic properties and misuse via intra-arterial injection has been associated with tissue damage and subsequent amputation. Temazepam-d5 is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

Uses

Temazepam (Phenyl D5) is labelled Temazepam (T017200) which is an intermediate-acting 3-hydroxy hypnotic of the benzodiazepine class of psychoactive drugs. Temazepam has anxiolytic (anti-anxiety), anticonvulsant, and skeletal muscle relaxant properties.

References

[1] SHANLIN FU. Reduction of temazepam to diazepam and lorazepam to delorazepam during enzymatic hydrolysis[J]. Analytical and Bioanalytical Chemistry, 2011, 400 1: 153-164. DOI: 10.1007/s00216-011-4723-y
[2] D.M. NOTT . Intra-arterial injection of temazepam in drug abusers[J]. European journal of vascular surgery, 1993, 7 1: Pages 87-89. DOI: 10.1016/s0950-821x(05)80550-x
[3] GERALD FX FEENEY MB BCH BAO FRACP  Harry H G M B F. Digit loss following misuse of temazepam[J]. Medical Journal of Australia, 2002, 176 8: 380. DOI: 10.5694/j.1326-5377.2002.tb04460.x

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