1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE Chemical Properties

Melting point:

153 °C

Boiling point:

452.3±45.0 °C(Predicted)

Density 

1.15±0.1 g/cm3(Predicted)

solubility 

DMSO: Slightly soluble: 0.1-1 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml

form 

Solid

pka

3.62±0.50(Predicted)

color 

Light yellow to brown

1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE Usage And Synthesis

Uses

Deschlorodiazepam is an analytical reference standard categorized as a benzodiazepine[1][2].

References

[1] Basile AS, et al. Brain concentrations of benzodiazepines are elevated in an animal model of hepatic encephalopathy. Proc Natl Acad Sci U S A. 1990 Jul;87(14):5263-7. DOI:10.1073/pnas.87.14.5263

[2] Sternbach LH, et al. Quinazolines and 1,4-benzodiazepines. 64. Comparison of the stereochemistry of diazepam with that of close analogs with marginal biological activity. J Med Chem. 1974 Mar;17(3):374-7. DOI:10.1021/jm00249a032

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